SRM University-AP, Andhra Pradesh is organizing University Distinguished Lecture Series. The first edition of the series is arranged on October 17, 2020, at 3 p.m., where Prof Ajay K Sood, Fellow of the Royal Society, FRS and Honorary Professor, Indian Institute of Science (IISc), Bengaluru, will be delivering a lecture on “Doing Science Without Borders”. In the recent times, humanity is facing several challenges such as the Covid-19 pandemic, climate change, and energy and food crises. Scientific and evidence-based inputs from various disciplines of natural science, engineering, as well as humanities is essential for the world to thrive.

This inter-disciplinary approach with active collaboration amongst experts across different spheres will assist in synthesizing a complete understanding of the issues. Prof Ajay K Sood will speak on his recent works such as “Emergent phenomena of flocking seen in birds, fishes and humans”, “Machine learning in understanding a few century-old problem of devitrification of glasses”, and “Making of nanoscale bacterial heat engines”. Drawing examples from his aforementioned works, Prof Ajay K Sood will narrate the power of collaboration in doing creative basic science.

Registration Link: https://bit.ly/srmapUDL01     (Registration Closed)

SRM University-AP, Andhra Pradesh along with Illinois Institute of Technology, Chicago, USA, is delighted to organize a webinar on “Education Opportunities at Illinois Institute of Technology, Chicago, USA”. The session will provide insights on the Twinning programme ideal for the current first and second year students, along with the Integrated Master’s programme that would be beneficial for the current third and final year students. Students are encouraged to participate in the webinar on October 16, 2020 at 5 p.m. for obtaining further information on the programmes, benefits of the programmes, and application process.

Registration Link: Please Click Here

For further details, Contact Dr. Sunil Chinnadurai

Connecting the dots between Mathematics and Physics of the hydrodynamic instability known as Viscous Fingering (VF)

DST, Government of India, sanctioned a total outlay of Rs.14.63 lakhs to Dr Tapan Kumar Hota, Assistant Professor, Department of Mathematics, SRM University-AP, Andhra Pradesh, for pursuing research on “Mathematical analysis and Adjoint Based Stability for a Coupled Convection-Diffusion equation in Miscible Displacement”. Hydrodynamic Stability (Instability) is a study of an equilibrium point subject to small and/or medium disturbances. This assists in understanding several complicated natural phenomena such as fluid transition from laminar to turbulent, chemical mixing, formation of cloud, and others. The available stability analysis is unable to address the early-time evolution of the VF process. The early-time behaviour of the system helps us to choose the parameters that are responsible for the long-time behaviour of the coupled PDEs. To achieve the target, we need to address the linear stability of the system from the study of the singular-value-decomposition instead of traditional eigenvalue analysis. As the system is non-autonomous, the eigenvectors/eigenvalues may not be physically relevant. Further, it is required to confirm our linear stability analysis by mathematical analysis of the coupled non-linear PDEs.

‘The nonmonotonic viscosity profile when a high mobile fluid is displacing a less mobile fluid. There is a potentially unstable region, where the viscosity increases in the flow direction, followed in the downstream direction by a potentially stable region, where the viscosity decreases in the flow direction. The disturbance structure is computed using the singular-value decomposition of the propagator matrix. Reference: Hota & Mishra, Journal of Fluid Mech, Vol. 856, pp:552-579, 2018.’

Dr Tapan is keen on studying other branches of science to provide the correct mathematical approach to address the issues. His project will address one of the hydrodynamic instabilities known as viscous fingering (VF). It forms when a high mobile fluid displaces a low mobile fluid. It has enormous implications in the field of Chemical Engineering Science, Petroleum Engineering, Chromatography, and Oil Extraction process. He explains, “I will study this instability from a mathematician’s point of view, more precisely, to address the mathematical analysis of coupled partial differential equations (PDEs). The system that governs the VF is non-autonomous and there is no readily available stability analysis that can represent Physics, based on robust mathematical analysis. My aim is to connect the dots between mathematics and physics of the VF.”

Infrastructure and laboratory facilities are crucial to conduct research. Upon receiving approval from a prestigious organization like SERB (Science and Engineering Research Board), Govt. of India, Dr. Tapan is entitled to this unique opportunity to serve the scientific community. He divulges, “The award is not only a recognition to me but also to the SRM University, AP. The University will be more visible in the world of research and can attract more eminent scientists and researchers to make the University their second home.” Quoting Master Oogway, ‘Yesterday is history, Tomorrow is a mystery… Today is a gift, that’s why it is called present.’, Dr Tapan is eager to commence working on his project at the earliest, and looks forward to enjoying the process of accomplishing the task.

Pursuit of discovering new drug molecules to combat diseases

Dr Writoban Basu Ball, Assistant Professor, Department of Biological Sciences, received an outlay of Rs.26.34 lakhs from DBT, Government of India to pursue research on “Targeting Kennedy pathway of cellular phosphatidylethanolamine biosynthesis as a common therapeutic strategy against protozoan parasites like Leishmania donovani, Trypanosoma brucei and Entamoeba histolytica.” Disease-causing intracellular parasites present serious health challenges, which could be fatal if left untreated. For example, Leishmania donovani and Trypanosoma brucei are the causative agents of visceral leishmaniasis and sleeping sickness, respectively. Entamoeba histolytica causes amoebiasis and 100,000 people die each year world-wide from amoebiasis-related complications. The current treatment regimen against these diseases consists of drugs that possess severe toxicity and drug resistance. Toxicity is detrimental to health and drug-resistance causes unresponsiveness of the drug to the parasite, rendering the drug ineffective. Therefore, it has become imperative to discover new drug molecules to combat these diseases.

In his study, Dr Writoban proposes to repurpose an FDA-approved drug meclizine, which can be used as a potential drug against dreadful parasitic infections. He explains. “One rational way to discover new and effective drugs entails identifying pharmacological targets against unique yet essential parasite metabolic pathways which are either absent or redundant in hosts (in the present case humans). One such central metabolic pathway in L. donovani, T. brucei, and E. histolytica is the Kennedy pathway for the biosynthesis of phosphatidylethanolamine (PE), a major lipid molecule of the cell. Without the presence of this lipid molecule, the cellular membranes (plasma membrane, organellar membranes) cannot form. Therefore, the Kennedy pathway is indispensable to parasite survival. On the contrary, in humans, although the Kennedy pathway is present, other pathway of PE biosynthesis is predominant. Hence, the Kennedy pathway offers a potential target to disrupt PE biosynthesis in these parasites without causing any side effects in the human host. In this context, meclizine, an over the counter anti-nausea drug, has been shown to disrupt the Kennedy pathway.”

Dr Writoban’s research is oriented to find safe cures for dreadful parasitic diseases that mostly plagues the underprivileged section of the developing countries like India, and countries of the sub-Saharan Africa. He believes, “The successful implementation of the proposed research scheme would benefit a lot of underprivileged people belonging to the underdeveloped and developing countries, as well as reduce the disease burden of those countries.” Further, Dr Writoban emphasizes, “Getting the grant is only the job half done. I would like to guide this proposal to a fruitful completion so that it can benefit people who need it most. I really want to take this project beyond the bounds of a mere academic exercise.

Navratri is around the corner, and the Department of Student Affairs, SRM University-AP, Andhra Pradesh is initiating Natyaswara on October 23-24, 2020. Marking the beginning of the auspicious occasion, and to uphold the spirit of festivities, the inter-college dancing and singing competition will enable the students to rejoice. Students are implored to participate in the competition, and showcase their skills in this traditional art form to win the prizes worth Rs. 10000 (Dancing: 1st Prize- Rs. 2000; 2nd Prize- Rs. 1500; 1st consolation prize- Rs. 500; 2nd consolation prize- Rs. 500; 3rd consolation prize: Rs. 500 & Singing: 1st Prize- Rs. 2000; 2nd Prize- Rs. 1500; 1st consolation prize- Rs. 500; 2nd consolation prize- Rs. 500; 3rd consolation prize: Rs. 500).

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