- Biocatalysis/ Biotransformation
- Protein/enzyme engineering
- Applications of enzymes in green chemistry and sustainable practices
Experience top of the world living and learning at SRM University-AP
+91-863-2343000
080-6988-6999 (admissions)
Email: admissions@srmap.edu.in
SRM University-AP, Neerukonda,
Mangalagiri Mandal, Guntur District, Andhra Pradesh - 522240
- November 2022-October 2024: Postdoctoral research fellow, Toulouse Biotechnology Institute, Toulouse, France.
- October 2021-October 2022: Postdoctoral research fellow, CEA-Genoscope (Centre National de Séquençage), Paris, France.
- January 2019- September 2021: Associate staff technologist, Praj Matrix R & D centre, Praj Industries Limited, Pune, India.
- December 2016- December 2018: Research scientist, Quintessence Fragrances Private Limited, India.
- Our lab focuses on understanding enzyme catalysis, structure-function relationships, and their industrial applications.
- Enhancing enzyme properties through enzyme engineering techniques, including rational design and directed evolution.
- Utilization of enzymes in organic synthesis, biofuel and perfume production, and plastic degradation within the framework of green chemistry and sustainability.
- 2009: CSIR-NET (LS): CSIR-UGC
- 2009: ICMR-Junior Research Fellowship, Indian Council of Medical Research.
- 2008: Received University of Mumbai scholarship for academic excellence in first year of post-graduation (M.Sc).
- 2024- present: Member of “European Society of Applied Biocatalysis (ESAB)”.
Research articles:
- Dipesh D. Jadhav, Oceane Toure, Anne Zaparucha*, Magali Remaud-simeon*. Rational engineering of thermophilic CoA ligase from Thermaerobacter subterraneus for small lactam synthesis. 2024 (Manuscript under preparation).
- Nikhil Ambatkar †, Dipesh D. Jadhav†, Somnath Nandi, Pramod Kumbhar*, and Phaneeswara-Rao Kommoju*. Optimized process for the production of fungal peroxidases and efficient saccharification of pretreated rice straw. Bioresource technology reports,17, 2022, 100913. (†-Authors contributed equally).
- Nikhil Ambatkar, Dipesh D. Jadhav, Apoorva Deshmukh, Parnal Sattikar, Geetanjali Wakade, Somnath Nandi, Pramod Kumbhar*, and Phaneeswara-Rao Kommoju*. Functional screening and adaptation of fungal cultures to industrial media for improved delignification of rice straw. Biomass and bioenergy, 155, 2021, 106271.
- Harshal S. Patil, Dipesh D. Jadhav†, Ajay Paul †, Fayaj Mulani, Shrikant J. Karegaonkar, H.V. Thulasiram*. Regioselective and efficient enzymatic synthesis of antimicrobial andrographolide derivatives. Bioorganic & Medicinal Chemistry Letters, 28, 6, 2018,1132-1138. (†- Authors contributed equally).
- Harshal S. Patil, Dipesh D. Jadhav†, Ajay Paul †, Fayaj Mulani, Shrikant J. Karegaonkar, H.V. Thulasiram*. Lipase catalyzed synthesis of antimicrobial andrographolide derivatives. Data in Brief, 18, 2018, 1134-1141.
- Kedar Limbkar, Ankita Dhenge, Dipesh D. Jadhav, H. V. Thulasiram, Vaijayanti Kale, Lalita Limaye*. Oral feeding with polyunsaturated fatty acids fosters hematopoiesis and thrombopoiesis in healthy and bone marrow-transplanted mice. The Journal of Nutritional Biochemistry, 47, 2017, 94-105.
- Kedar Limbkar, Ankita Dhenge, Dipesh D. Jadhav, H. V. Thulasiram, Vaijayanti Kale, Lalita Limaye*. Data on the effect of oral feeding of Arachidonic acid or Docosahexanoic acid on hematopoiesis in mice. Data in brief, 14, 2017,551-557.
- Dipesh D. Jadhav, Harshal S. Patil, Patil S. Chaya and H. V. Thulasiram*. Fungal mediated kinetic resolution of racemic acetates to (R)-Alcohols by Fusarium proliferatum. Tetrahedron Letters, 57, 41, 2016, 4563-4567.
- Swati P. Kolet, Dipesh D. Jadhav, Balaraman Priyadarshini, Bhagyashree N. Swarge, H. V. Thulasiram*. Fungi mediated production and practical purification of (R)-3-quinuclidinol, Tetrahedron Letters, 55, 43, 2014, 5911–5914.
- Saikat Haldar, Balaji Kale, Dipesh D. Jadhav, H.V. Thulasiram*. Lipase mediated separation of triterpene isomers, α- and β-amyrins, Tetrahedron Letters, 55, 19, 2014, 3122–3125.
- N. Sathish Yadav, M.G. Adsul, K.B. Bastawde, Dipesh D. Jadhav, H.V. Thulasiram, D.V. Gokhale*. Differential induction, purification and characterization of cold active lipase from Yarrowia lipolytica NCIM 3639, Bioresource Technology, 102, 22, 2011, 10663-10670.
Review articles
- Pranjit Kumar Bora, Phirose Kemprai, Sajjad Hussain, Rinku Baishya, Dipesh Jadhav, Saikat Haldar*. Mushroom-based biocatalysts for the synthesis of aroma and flavours from exogenous organic molecules: a review of two decades. International Journal of Food Science and Technology, 59, 1, 2024, 84-94.
Patents published/filed:
- Dipesh D. Jadhav, Nilofer Jahan K. Siddiqui, Swati P. Kolet, H. V. Thulasiram*. A process of chiral resolution of cyclic and acyclic acetates to enantiomerically pure (R)-alcohols. 2018. Publication number: US10023891, EP3063281B1, WO2015063796A2.
- Pramod S. Kumbhar, Phaneeswara Rao Kommoju, Apoorva Deshmukh-kambale, Parnal Sattikar, Dipesh D. Jadhav, Geetanjali S. Wakade, Nikhil D. Ambatkar. An enzymatic pre-treatment method for efficient saccharification of lignocellulosic materials. 2022. Publication number: WO2022234597A1, US20240191268A1.
- Dipesh D. Jadhav, Anne Zaparucha*. Method and kit for the enzymatic degradation of poly(allyl diglycol carbonate). [Filed: 2024]. Publication number: EP23306473.
- Dipesh D. Jadhav, Anne Zaparucha*. Method and kit for the enzymatic degradation of polythiourethanes. [Filed: 2024]. Publication number: EP23306475.
Conference attended:
- "Club Biocatalyse en Synthese Organique (CBSO)-2022" conference in Biocatalysis at Paris, France in June 2022.
- "NextGenBiocat 2.0” conference in Biocatalysis at TU Delft, Netherlands in April 2022.
Oral presentation:
- “Chiral resolution of important flavour and fragrance compounds using Lipases.” Dipesh D. Jadhav, Niloferjahan K. Siddiqui, Swati P. Kolet, H. V. Thulasiram*. given in the Symposium “Biodesign India 1.0” held by University of Kerala, India in October 2010.
Poster presentations:
- “One pot tandem biocatalytic resolution of esters to enantiopure (R)-alcohol catalysed by versatile fungus Fusarium proliferatum NCIM 1105”. Dipesh D. Jadhav, Nilofer Jahan K. Siddiqui, H. V. Thulasiram* in “The International Symposium on Bioorganic Chemistry (ISBOC)-2015” held in IISER Pune, India in January 2015.
- “Chiral resolution of important flavour and fragrance compounds using Lipases.” Dipesh D. Jadhav, Nilofer Jahan K. Siddiqui, H. V. Thulasiram* in international symposium “Indo-Mexico workshop on Biotechnology: beyond borders” organized by CSIR-NCL, Pune and CINVESTAV Mexico in October 2013.
- E-mail id: dipesh.d@srmap.edu.in